Final answer:
The DEA Form 222 is mandatory for ordering "Schedule I" and "Schedule II" controlled drugs. Registered entities with the DEA must use this triplicate form to legally handle these controlled substances. The Center for Drug Evaluation and Research oversees drug approval, including new and generic drugs, through the NDA process.
Step-by-step explanation:
The specific FORM required to order "Schedule I" and "Schedule II" controlled drugs is the DEA Form 222. This form is a triplicate order form, also known as Controlled Substances Order Form, which is used by entities that are registered with the Drug Enforcement Administration (DEA). The process is regulated to ensure the lawful handling of these substances which have a high potential for abuse and are subjected to strict regulatory control. The Center for Drug Evaluation and Research (CDER) governs how drugs, including new and generic drugs are approved and monitored.
While the question at hand deals with the ordering of controlled substances rather than the approval process it's important to note that new drugs must go through an extensive approval process known as a New Drug Application (NDA) before they are available by prescription or over-the-counter (OTC). All new medications are deemed available by prescription by default, until an OTC status is obtained after an NDA approval.