Final answer:
Peripheral edema at birth can cause cardiovascular abnormality later, leading to systemic edema.
Step-by-step explanation:
Peripheral edema at birth can cause cardiovascular abnormality later. Edema is the accumulation of excess water in the tissues, which can lead to increased pressure within the veins and promote the flow of fluids out of the capillaries and into the interstitial fluid. This excess tissue fluid around the cells can result in systemic edema, seen as swelling over large areas of the body, particularly the lower extremities.