Answer:
1- The CRISPR-Cas system
2- Genetically modified organisms raise concerns associated with allergic reactions, horizontal gene transfer and outcrossing
Step-by-step explanation:
The CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats)-Cas (CRISPR-associated) technology is widely used in medicine and research. The CRISPR-Cas is a versatile RNA-programable genome editing system capable of introducing genetic modifications at target DNA sequences. This technology is based on the natural bacterial immune system that cleaves bacteriophages and plasmid DNA sequences. Moreover, Genetically Modified Organisms (GMO) have historically raised three major concerns on human health: 1-the allergenicity of GMO foods, 2-the ability that GMOs might have to insert genes through horizontal transfer and 3-outcrossing between GMOs and (genetically) unmodified crops, which are further consumed as non-GM foods.