Question

Describe the mismatch repair process of bacteria (pay attention at the ways in which the daughter and parent strand are recognized by repair system).

A) Mismatch repair recognizes mismatches based on the parent strand's methylation pattern.
B) Mismatch repair identifies errors by comparing the daughter strand to a reference genome.
C) Mismatch repair operates independently of parent strand recognition.
D) Mismatch repair relies on RNA markers for identifying errors in the daughter strand.

Answer 1

The mismatch repair process in bacteria involves recognizing and correcting errors during DNA replication by using the parent strand's methylation pattern as a recognition factor.

Step-by-step explanation:

The mismatch repair process in bacteria involves the recognition and correction of errors that occur during DNA replication. The correct answer to the question is A) Mismatch repair recognizes mismatches based on the parent strand's methylation pattern. In E. coli, the DNA is hemimethylated, with the parental strand methylated and the newly synthesized daughter strand not methylated initially. Proteins Muts, MutL, and MutH bind to the hemimethylated site where the incorrect nucleotide is found. MutH cuts the nonmethylated strand, and an exonuclease removes the part of the strand containing the incorrect nucleotide. The gap is then filled in by DNA pol III and ligase.