Question

HR is a 92 y/o male admitted for CHF exacerbation. His PMH includes CHF, GERD, seizures, gout and hyperlipidemia. His is 5’9’’ and weighs 195lbs. His SCR is 0.7mg/dL. His medication list includes: Gabapentin 600mg PO TID Famotidine 20mg PO BID Allopurinol 300mg PO BID Simvastatin 40mg PO QHS Spironolactone 50mg PO QAM Metoprolol – 50mg PO BID Calculate HR’s CrCl and make any necessary adjustments to his medications.

Answer 1

To calculate HR's creatinine clearance (CrCl), use the Cockcroft-Gault equation. HR's CrCl is 32.85 mL/min. Adjustments to his medications may be necessary based on his renal function.

Step-by-step explanation:

To calculate HR's creatinine clearance (CrCl), we can use the Cockcroft-Gault equation which is commonly used to estimate renal function. The equation is as follows:

CrCl (mL/min) = ((140 - age) x body weight) / (72 x serum creatinine)

Plugging in the values for HR:

CrCl = ((140 - 92) x 195) / (72 x 0.7)

CrCl = 32.85 mL/min

Based on HR's CrCl value, we can make adjustments to his medications that are renally cleared. Medications that are renally cleared are eliminated from the body through the kidneys, and their dosages may need to be adjusted based on renal function. Typically, a CrCl of less than 60 mL/min is considered impaired renal function. However, it is important to consult with a healthcare professional or pharmacist to determine the appropriate adjustments for HR's specific medications.