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Pathogenesis of alcohol-induced hepatic steatosis

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Final answer:

Alcohol-induced hepatic steatosis, or fatty liver disease, is caused by chronic excessive alcohol consumption. The pathogenesis involves the alcohol dehydrogenase system and the accumulation of fatty acids in the liver. Metabolic disorders, infections, and cirrhosis can also contribute to fatty liver disease.

Step-by-step explanation:

Alcohol-induced hepatic steatosis, also known as fatty liver disease, occurs due to chronic excessive consumption of alcohol. This condition is characterized by the accumulation of fat in the liver. The pathogenesis involves the alcohol dehydrogenase system, where ethanol is broken down into acetaldehyde and then further degraded into acetate by acetaldehyde dehydrogenase. The excessive accumulation of acetaldehyde and fatty acids in the liver leads to the development of fatty liver disease. Other causes of fatty liver disease include metabolic disorders, infections, and cirrhosis.

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