Question

Alkaptonuria = autosomal-recessive deficiency of *homogentisic acid* dioxygenase (an enzyme involved in tyrosine metabolism), so it accumulates. Symptoms?

Answer 1

Alkaptonuria is a recessive genetic disorder that causes the accumulation of homogentisic acid in the body. Symptoms include darkened skin, brown urine, and joint damage.

Step-by-step explanation:

Alkaptonuria is a recessive genetic disorder caused by a deficiency of the enzyme homogentisic acid dioxygenase, which is involved in the metabolism of tyrosine. In this disorder, homogentisic acid accumulates in the body. The symptoms of alkaptonuria include darkened skin, brown urine, and joint damage.