216k views
4 votes
Explain what MALT and GIST. What is the medical therapy for GIST tumors?

User Bmartin
by
8.3k points

1 Answer

6 votes

Final answer:

MALT is a collection of lymphoid follicles in mucous membrane epithelia, specifically in the gastrointestinal tract. GIST tumors are treated with targeted therapy using tyrosine kinase inhibitors.

Step-by-step explanation:

MALT stands for Mucosa-Associated Lymphoid Tissue, which is a collection of lymphoid follicles found in the mucous membrane epithelia of various body parts, such as the gastrointestinal tract. MALT plays a significant role in immune responses against ingested substances. It contains specialized endothelial cells called M cells that transport material from the intestinal lumen to nearby follicles for immune responses.

GIST stands for Gastrointestinal Stromal Tumors, which are rare types of tumors that occur in the gastrointestinal tract. The medical therapy for GIST tumors often involves targeted therapy with tyrosine kinase inhibitors, such as imatinib mesylate or sunitinib malate. These medications block specific signaling pathways in cancer cells, helping to slow or stop tumor growth.

User Matskn
by
8.9k points