Final answer:
The true statement about mitral regurgitation is that it may be noted as a holosystolic murmur, which can occur from various factors, not just stiff leaflets or congenital malformations, and is not characterized by a prolonged PR interval on an electrocardiogram.
Step-by-step explanation:
Among the statements provided about mitral regurgitation, the true one is that it may be noted as a holosystolic murmur. The other statements are not accurate descriptions of mitral regurgitation. Mitral regurgitation is a condition where the mitral valve does not close properly during systole, allowing blood to flow backward from the left ventricle to the left atrium. This leads to a murmur that can be heard throughout systole, also known as a holosystolic murmur. It is not solely caused by stiff leaflets limiting flow, nor is it only due to congenital malformations, as it can result from various factors such as mitral valve prolapse, rheumatic heart disease, or damage to the chordae tendineae. Additionally, a prolonged PR interval on an electrocardiogram is not a specific finding associated with mitral regurgitation.