Final answer:
Lyme disease, suggested by the symptoms of a target lesion and flu-like symptoms, is managed pharmacologically with antibiotics such as doxycycline, amoxicillin, or cefuroxime.
Step-by-step explanation:
The symptoms described in the question, including a target lesion with central clearing, severe headache, malaise, fatigue, and generalized musculoskeletal pain, are indicative of Lyme disease, which is a bacterial infection transmitted by ticks. Pharmacologic management of Lyme disease typically includes antibiotics such as doxycycline, amoxicillin, or cefuroxime. Treatment should begin promptly to prevent further complications, and the duration of the antibiotic course may vary depending on the stage and severity of the disease.
Given the age of the patient and the location of the lesion, doxycycline is usually the preferred antibiotic for those who are 8 years and older. However, for a child under 8, amoxicillin is generally used. It is essential to consult a healthcare professional for the appropriate diagnosis and treatment.