Question

Explain the mechanism of action of Naloxone, and how is it typically used in clinical practice? What adverse effects may occur with its administration?

Answer 1

Naloxone is an opiate antagonist that antagonizes the actions of morphine at all its receptors. It is used to reverse respiratory depression caused by narcotics and is administered via the parenteral route. Naloxone has a short duration of action.

Step-by-step explanation:

Naloxone is an opiate antagonist that works by antagonizing the actions of morphine at all its receptors. When administered to normal individuals, it does not produce analgesia, euphoria, or respiratory depression. However, when given to narcotic-dependent individuals, it rapidly precipitates withdrawal. Naloxone is commonly used in clinical practice for the reversal of respiratory depression following acute narcotic intoxication and in newborns of mothers who have received narcotics. Its administration should be done via the parenteral route, and it has a short duration of action.324