Final answer:
The answer highlights gender, marital status, living arrangement, and study location as significant demographic determinants of loneliness that affect social interactions and feelings of connection or isolation.
Step-by-step explanation:
The significant demographic determinants of loneliness mentioned are gender, marital status, living arrangement, and study location. Demography studies populations and their characteristics, where factors such as gender and marital status often influence social interactions and tendencies towards loneliness.
Living arrangements, which can include residing alone or with others, also contribute to social opportunities and feelings of connection or isolation. The study location can affect access to social networks and activities that mitigate loneliness. These factors are often central in understanding the socio-demographic aspects of loneliness in various populations.