Question

What 3 transport location ways do multi-subunit tethers act upon (most common)?

A. Golgi to ER, Golgi to endosomes, ER to plasma membrane
B. Golgi to lysosomes, Golgi to endosomes, ER to Golgi
C. Golgi to plasma membrane, Golgi to endosomes, ER to Golgi
D. ER to Golgi, Golgi to endosomes, Golgi to lysosomes

Answer 1

Multi-subunit tethers facilitate transport from the endoplasmic reticulum to the Golgi apparatus, from the Golgi apparatus to endosomes, and from the Golgi apparatus to lysosomes.

Step-by-step explanation:

The three most common ways multi-subunit tethers act upon transport locations are:

• From the endoplasmic reticulum (ER) to the Golgi apparatus
• From the Golgi apparatus to endosomes
• From the Golgi apparatus to the lysosomes

Transport vesicles move from the ER to the Golgi apparatus for initial processing. The Golgi then modifies proteins and lipids, sends them to endosomes for further sorting, or directs them to lysosomes through the trans-Golgi network. The result of these modifications can include glycosylation or phosphorylation, which serve as sorting signals to route proteins to their proper destinations, such as endosomes or lysosomes.