Final answer:
Squanto, a member of the Pawtuxet tribe of the Wampanoag Confederacy, played a crucial role in helping the Pilgrims and acted as an interpreter for them.
Step-by-step explanation:
The first Indian to treat Regina kindly when they reached the village is not specified in the given information.
However, in the context of the information provided, there are references to interactions between the Pilgrims and the Indians in the early settlement of Plymouth.
Squanto, a member of the Pawtuxet tribe of the Wampanoag Confederacy, played a crucial role in helping the Pilgrims and acted as an interpreter for them. His efforts and the treaty between the Pilgrims and Wampanoag sachem Massasoit in 1621 established peaceful relations between the English and the Indians.