Question

Which of the following information could not be gained from a genomic study of a pathogenic strain and a nonpathogenic strain of the same species of bacteria?

A. identity of possible virulence genes present in the pathogenic strain but not present in the nonpathogenic strain
B. presence of pathogenicity islands in the pathogenic strain
C. genes that are expressed when the pathogenic bacteria infect a host
D. lack of metabolic genes in both strains that would make them hard to grow in culture

Answer 1

A genomic study cannot provide information on genes expressed when the pathogenic bacteria infect a host, but it can identify virulence genes, pathogenicity islands, and metabolic gene deficiencies.

Step-by-step explanation:

The information that could not be gained from a genomic study of a pathogenic strain and a nonpathogenic strain of the same species of bacteria is C. genes that are expressed when the pathogenic bacteria infect a host. Genomic studies provide data on the presence, absence, and sequence of genes, but they do not directly inform us about gene expression in different environments, such as during infection. To determine gene expression, other techniques such as transcriptomic analysis are needed. Examples of data that could be obtained through genomic studies include A. the identity of possible virulence genes present in the pathogenic strain but not present in the nonpathogenic strain, B. the presence of pathogenicity islands in the pathogenic strain, and D. the lack of metabolic genes in both strains that would make them hard to grow in culture.