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Which bile acid-binding resins or sequestrants is the only one that has been shown to reduce CVD events by 20%.

User Pacey
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Final answer:

The information provided does not specify which bile acid-binding resin reduces CVD events by 20%. Cholestyramine, a bile acid sequestrant, is well-known for its impact in studies, despite not being specifically mentioned. Treatment of hyperlipidemia typically involves medications and dietary changes, tailored to individual needs.

Step-by-step explanation:

The bile acid-binding resin that has been shown to reduce cardiovascular disease (CVD) events by 20% isn't specifically mentioned in the provided information. However, among bile acid sequestrants, cholestyramine has been studied and known for its impact on cardiovascular outcomes, particularly in the landmark study known as the Lipid Research Clinics Coronary Primary Prevention Trial (LRC-CPPT). While this data is not included here, it is historically significant for illustrating the benefit of bile acid sequestrants on cardiovascular risk in a research context. Generally, bile acid-binding resins, also known as bile acid sequestrants, work by binding bile acids in the intestine, preventing them from being reabsorbed. This action requires the liver to use up more cholesterol to produce new bile acids, thereby lowering the cholesterol level in the blood.

Despite the effectiveness of these drugs in lowering cholesterol levels, the reduction in CVD events is not as direct and depends on multiple factors including the individual patient's health profile and whether they are used in conjunction with other treatments like statins, which are more commonly associated with reducing CVD events. To effectively manage hyperlipidemia and decrease cardiovascular risk, patients are often advised to make dietary modifications and, where necessary, are prescribed medications such as statins, fibrates, ezetimibe, niacin, and bile acid sequestrants. Therapy is tailored to patient-specific lipid profiles, risk factors, and response to treatment. Monitoring the effectiveness of these treatments usually involves regular blood lipid profile tests.

User Julien Silland
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