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What three things make up gastric juice? How acidic is it?

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Final answer:

Gastric juice is comprised of water, hydrochloric acid, and digestive enzymes like pepsinogen, which becomes pepsin in the stomach's acidic environment, typically with a pH of 1.0 to 2.5. It is essential for the initial breakdown of proteins.

Step-by-step explanation:

Gastric juice is a crucial component of the digestive process, comprising primarily water, hydrochloric acid (HCl), and digestive enzymes. One of the main enzymes is pepsinogen, which is converted to its active form, pepsin, upon exposure to the acidic environment of the stomach. Hydrochloric acid is secreted by the stomach lining, and it plays a vital role in both denaturing proteins and converting pepsinogen to pepsin. The pH of gastric juice is highly acidic, typically around 1.0 when freshly secreted, but it can rise to between 1.5 and 2.5 once it mixes with the stomach contents. The process of gastric secretion can be influenced by neural and hormonal signals, and occurs in three phases: cephalic, gastric, and intestinal, which can overlap during digestion.

Gastric juice's acidity is important as it helps in the initial breakdown of food, setting the stage for further digestion in the small intestine, where the environment is less acidic due to the neutralizing effect of pancreatic juice. Understanding how gastric juice functions and its composition can be critical for diagnosing and treating various gastrointestinal conditions.

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