Final answer:
DEA Form 222 must be used within 60 days of execution by the purchaser to be valid for ordering Schedule I and II controlled substances according to CSA regulations.
Step-by-step explanation:
The question pertains to the DEA Form 222, which is a document used in the United States for the ordering of Schedule I and Schedule II controlled substances. According to the Controlled Substances Act (CSA) regulations enforced by the Drug Enforcement Administration (DEA), no DEA Form 222 is valid for more than 60 days after its execution by the purchaser. This means that the purchaser must use the form to order and receive the controlled substances within this timeframe, otherwise the form becomes unusable for purchasing purposes.