Final Answer:
The initial presentation of acute rheumatic fever is preceded by a group A streptococcal infection. Option 2 is the answer.
Step-by-step explanation:
Acute rheumatic fever (ARF) is an inflammatory condition that may develop following an untreated or inadequately treated group A streptococcal infection, typically strep throat. The immune response triggered by the streptococcal infection can lead to an autoimmune reaction affecting various organs, including the heart, joints, skin, and nervous system. This condition often arises 2-4 weeks after the initial streptococcal infection. The symptoms include fever, joint pain, skin rash, and potential cardiac complications. Unlike some other diseases, the initial presentation of acute rheumatic fever is not preceded by exposure to mites, chickenpox, or a viral illness.
Option 2 is the answer.