Final answer:
The major pathway for catabolism of saturated fatty acids in mitochondria is beta-oxidation.
Step-by-step explanation:
The major pathway for catabolism of saturated fatty acids in mitochondria is called beta-oxidation.
This process involves the breakdown of fatty acids into acetyl CoA molecules, which can then enter the Krebs cycle to produce ATP.
During beta-oxidation, the fatty acids are converted into fatty acyl CoA molecules in the cytoplasm, then transported into the mitochondria where they undergo a series of reactions to produce acetyl CoA.