Final answer:
The most common causes of cirrhosis in the U.S. are alcohol abuse and Hepatitis C. Cirrhosis leads to the irreversible replacement of liver cells with fibrous tissue, often requiring a liver transplant in advanced stages.
Step-by-step explanation:
The most common cause of cirrhosis in the U.S. is alcohol abuse and Hepatitis C. Cirrhosis is characterized by the formation of fibrous tissue in the liver, which replaces dead liver cells. These liver cells can die due to various reasons such as viral hepatitis, alcoholism, or exposure to liver-toxic chemicals. Chronic liver failure often results from cirrhosis, and once it occurs, the condition is generally irreversible. Treatment focuses on preventing progression and managing complications, with a liver transplant being the last resort in advanced stages.
Hepatitis B is another cause of liver inflammation and may lead to cirrhosis, but the primary drivers in the U.S. are alcohol abuse and Hepatitis C. Hepatitis C is particularly concerning as it can remain asymptomatic for years and lead to significant liver damage over time.