Immature neutrophils have decreased Fc receptors (CD-16), resulting in reduced functionality and a weaker immune response.
The statement is True. Immature neutrophils, also known as band neutrophils or left shift neutrophils, are characterized by a decreased expression of Fc receptors, specifically CD-16. CD-16 is an important receptor found on the surface of mature neutrophils that aids in the recognition and phagocytosis of pathogens.
With decreased CD-16 expression, immature neutrophils have reduced functionality and are less efficient in carrying out their immune functions. They have a diminished ability to engulf and destroy pathogens through phagocytosis, leading to a weakened immune response.
For example, in a condition such as bacterial infection, an increase in the presence of immature neutrophils (left shift) in the blood can indicate an ongoing immune response, but their reduced function may contribute to a compromised ability to eliminate the infectious agent.
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