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Familial cases of ALS may be associated with zinc-copper superoxide dismutase 1 (SOD1) mutations, which leads to free radical injury in neurons. What is the association between familial cases of ALS and SOD1 mutations?

1) Familial cases of ALS are not associated with SOD1 mutations
2) Familial cases of ALS are associated with SOD1 mutations
3) Familial cases of ALS are associated with other types of mutations
4) Familial cases of ALS are not associated with any mutations

1 Answer

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Final answer:

Familial cases of ALS are associated with SOD1 mutations, which lead to free radical injury in neurons.

Step-by-step explanation:

Familial cases of ALS are associated with zinc-copper superoxide dismutase 1 (SOD1) mutations. These mutations result in free radical injury in neurons, leading to the development of ALS.

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