Question

A nurse obtains an allergy history from a client based on the understanding that which class is associated with a cross-sensitivity reaction with sulfonamides?

A) Penicillins
B) Macrolides
C) Cephalosporins
D) Fluoroquinolones

Answer 1

Cephalosporins are the class of antibiotics that may have a cross-sensitivity reaction with sulfonamides due to similar sulfur-containing structures that can cause allergic reactions. The Correct Answer is Option. C.

Step-by-step explanation:

The class of antibiotics associated with a cross-sensitivity reaction with sulfonamides is Cephalosporins. This is because both sulfonamides and cephalosporins contain a similar sulfur-containing chemical structure, which can elicit an allergic response in individuals who are allergic to sulfa drugs.

Cephalosporins, like penicillin, are ß-lactam antibiotics and have a broad spectrum of action, but due to the structural similarities, there is a risk of cross-reactivity with sulfonamides.

It is essential for nurses and other healthcare professionals to obtain a thorough allergy history to avoid administering medications such as cephalosporins to patients with known sulfa allergies, thereby preventing possible severe allergic reactions.