The Pueblo Revolt of 1680 was a significant uprising by indigenous Pueblo people against Spanish colonization in the region that is now the southwestern United States. The main grievances leading to the revolt included forced labor, religious suppression, and the imposition of Spanish cultural practices. The big event that sparked the rebellion was the coordinated uprising on August 10, 1680, when the Pueblo people, led by leaders like Popé, simultaneously attacked Spanish settlements, missions, and military posts, expelling the Spanish from the region for a significant period.