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Which of the following conditions could produce rickets?

a. Metabolic deficiency of parathyroid hormone.
b. Impairment of conversion of vitamin D to its active form.
c. Inability of the active form of vitamin D to act on its target tissue.

1 Answer

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Final answer:

Conditions such as the impairment of conversion of vitamin D to its active form and the inability of its active form to act on its target tissue can lead to rickets, which is a disorder causing improper bone development in children due to a vitamin D deficiency.

Step-by-step explanation:


Conditions that could produce rickets include: b. Impairment of conversion of vitamin D to its active form, and c. Inability of the active form of vitamin D to act on its target tissue. Rickets is characterized by improper bone development in children due to malabsorption of calcium and a deficiency in vitamin D. Vitamin D deficiency can lead to low serum phosphate (P) levels and defects in the calcification of bones. This condition is further compounded by inadequate sun exposure, poor dietary intake, or malabsorption issues that hinder the effective utilization of vitamin D and calcium for the healthy development of bones.

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