Final answer:
The identification of integral membrane proteins that span the entire membrane provided evidence that the static Davson-Danielli model was incorrect, leading to the acceptance of the dynamic Fluid Mosaic model proposed by Singer and Nicolson.
Step-by-step explanation:
Evidence Falsifying Davson-Danielli Model
One piece of evidence that falsified the Davson-Danielli model in support of the Singer-Nicholson model is the identification of integral membrane proteins. The Davson-Danielli model, also known as the sandwich model, proposed a static structure where proteins coat the polar heads of phospholipids, resembling a protein-lipid-protein sandwich. However, this model was replaced by the Singer and Nicolson's Fluid Mosaic model in 1972, which suggested that besides peripheral proteins binding to the membrane surfaces, many integral proteins actually span the membrane providing a fluid and dynamic structure.
The identification of these integral membrane proteins was inconsistent with the Davson-Danielli's rigid model and supported the idea that membrane proteins are not merely on the surface but are embedded throughout and can move within the phospholipid bilayer. This discovery highlighted the fluidity of the cell membrane, contributing to the acceptance of the Fluid Mosaic model as more accurate in describing the cell membrane's structure and functions.