Final answer:
The organisms most commonly responsible for acute suppurative otitis media are Streptococcus pneumoniae and Haemophilus influenzae, particularly in older infants and children younger than 14 years old.
Step-by-step explanation:
Most Common Organisms Causing Acute Suppurative Otitis Media
The most common organisms causing acute suppurative otitis media (AOM) in different age groups vary. Among neonates, the most common cause of AOM is Streptococcus pneumoniae, although other bacteria like Escherichia coli, Enterococcus spp., and group B Streptococcus species may also be involved.
In older infants and children up to 14 years old, AOM is most frequently caused by Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis. The strains of S. pneumoniae associated with AOM are usually encapsulated, while H. influenzae and M. catarrhalis strains involved do not possess a capsule. The pathogenicity in AOM arises from the inflammatory response induced by bacterial components like lipopolysaccharide (LPS) in gram-negative bacteria, leading to swelling, pus, and tissue damage within the middle ear.
The organisms most commonly responsible for acute suppurative otitis media are a) Streptococcus pneumoniae and Haemophilus influenzae.