Final answer:
Tolerance is the phenomenon where the body becomes used to the effect of a medicine and requires increasingly larger doses to produce the same effect.
Step-by-step explanation:
Tolerance is the phenomenon where the body becomes used to the effect of a medicine and requires increasingly larger doses to produce the same effect. For example, if a person regularly takes a pain medication, they may find that over time they need to take a higher dose in order to achieve the same level of pain relief.
This is a form of physiological dependence, meaning the body has adapted to the presence of the drug and has become less responsive to its effects. Tolerance can be a concern as it can lead to an increased risk of overdose if a person takes a dose that is higher than their body can handle.