Question

The globin within macrophages that have consumed RBCs is further broken down into ________ amino acids.

1) glycine
2) alanine
3) valine
4) leucine
5) isoleucine
6) phenylalanine
7) tyrosine
8) tryptophan
9) methionine
10) cysteine
11) histidine
12) lysine
13) arginine
14) proline
15) serine
16) threonine
17) asparagine
18) glutamine

Answer 1

The globin protein within macrophages that have consumed RBCs is broken down into amino acids, which include all 18 amino acids mentioned in the list. These amino acids are then recycled for the production of new proteins, such as new erythrocytes in the bone marrow.

Step-by-step explanation:

Within macrophages that have engulfed red blood cells (RBCs), the globin protein is metabolically broken down into its constituent amino acids. These amino acids are then recycled and used in the synthesis of new proteins, including the production of new erythrocytes by the bone marrow. The globin chain contains various amino acids including glycine, alanine, valine, leucine, isoleucine, phenylalanine, tyrosine, tryptophan, methionine, cysteine, histidine, lysine, arginine, proline, serine, threonine, asparagine, and glutamine. All of these amino acids can be generated through the breakdown of globin.

When hemoglobin that has not been phagocytized is broken down in the circulation, its alpha and beta chains release these amino acids. The iron from the heme group is either stored or transported to the bone marrow for reuse, while the non-iron part of heme is metabolized into waste products like biliverdin and bilirubin. Bilirubin is later converted into urobilinogen and stercobilin in the large intestine and eliminated from the body.