Final answer:
Coproporphyrinogen III is concerted to protoporphyrin in the process of heme synthesis, a key step in the production of hemoglobin in the bone marrow.
Step-by-step explanation:
Coproporphyrinogen III is converted to protoporphyrin in the process of heme synthesis. Heme is an essential component of hemoglobin and is synthesized in the reticuloendothelial cells (bone marrow). This process is crucial for the formation of hemoglobin as it involves the conversion of porphyrin to heme by the addition of iron.
The regulation of this pathway is tightly controlled with ALA synthase acting as a key regulatory enzyme. Excessive heme acts as a negative regulator for the synthesis of ALA synthase-I inhibiting its gene. Protoporphyrin III is an intermediate in this biosynthetic pathway and its conversion to heme involves several steps which are integral to the production of functional hemoglobin in erythrocytes.