Final answer:
NSAIDs can cause photosensitivity, necessitating avoidance of midday sun exposure to prevent skin damage such as sunburn, which can lead to an increased risk of skin cancer.
Step-by-step explanation:
NSAIDs can cause photosensitivity, which is an increased sensitivity to sunlight. When taking NSAIDs, individuals should avoid sun exposure during midday to minimize the risk. Photosensitivity can lead to skin reactions such as a sunburn or rashes. Sunburn is particularly caused by large exposures to UV-B and UV-C radiation, which can increase the likelihood of skin cancer. Tanning can occur following sunburn, as it is a defense mechanism where the body produces pigments to reduce exposure to living cells beneath the skin layers. It's important to remember that while some sunlight is necessary for vitamin D synthesis, too much exposure can be detrimental and can lead to skin damage such as sunburn.