Question

Which of the following is a method to prevent graft-versus-host disease (GVHD)?

1) Administering immunosuppressive drugs
2) Using irradiated blood products
3) Performing leukocyte depletion
4) Matching HLA antigens between donor and recipient

Answer 1

Matching HLA antigens between the donor and recipient is a method to prevent graft-versus-host disease (GVHD) in bone marrow transplants.

Step-by-step explanation:

Graft-versus-host disease (GVHD) can be prevented by matching HLA antigens between the donor and recipient. HLAs are human leukocyte antigens that play a crucial role in tissue transplantation. By closely matching the HLAs, the risk of rejection decreases. Administering immunosuppressive drugs, using irradiated blood products, and performing leukocyte depletion can all be part of the treatment and management of GVHD but don't specifically prevent it.