Final answer:
The liver is located directly inferior to the diaphragm in the epigastric, umbilical, and left hypochondriac regions of the abdomen. It anchors to the abdominal wall and diaphragm, suspends the stomach, and provides a pathway for structures connecting to the liver.
Step-by-step explanation:
The structure located directly inferior to the diaphragm in the epigastric, umbilical, and left hypochondriac regions of the abdomen is the liver.
The liver is a vital organ that anchors to the anterior abdominal wall and inferior border of the diaphragm. It also suspends the stomach from the inferior border of the liver and provides a pathway for structures connecting to the liver.