Final answer:
Lead II would be the best lead for monitoring a patient with ST segment changes suggesting an acute inferior wall myocardial infarction.
Step-by-step explanation:
The best lead for monitoring a patient with ST segment changes that suggest an acute inferior wall myocardial infarction would be lead II. Lead II represents the electrical activity in the inferior wall of the heart, which is where the ST segment changes are occurring. By monitoring lead II, medical professionals can track any further changes in the patient's ECG that may indicate worsening or improvement of the condition.