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If light chain rearrangement is productive (i.e., not out of frame), it leads to what?

a) Apoptosis
b) Anergy
c) Functional B cell receptor
d) Phagocytosis

User Krizzzn
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1 Answer

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Final answer:

Productive light chain rearrangement in B cell development leads to the creation of a functional B cell receptor, which is crucial for clonal expansion and the immune response.

Step-by-step explanation:

If light chain rearrangement is productive, meaning it occurs without any errors and the resulting antibody can be expressed, it leads to the production of a functional B cell receptor. This is a key step in B cell development, as the functional B cell receptor is needed for the B cell to participate in the immune response. When B cells successfully produce a functional B cell receptor, it signifies that the B cell is mature and can recognize specific antigens, which is essential for its role in the adaptive immune system. Additionally, this step is crucial for clonal expansion, ensuring that B cells with functional receptors are ready to proliferate and mount an immune response when an antigen is encountered.

User Jafari
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