Final answer:
Yes, there is publicly available simulation software for running simulations on how a substance affects bloodstream levels of a drug over time. Modeling and simulation are important tools in drug development.
Step-by-step explanation:
Yes, there is publicly available simulation software for running simulations on how a substance affects bloodstream levels of a drug over time. In drug development, modeling and simulation are important tools used to predict the pharmacokinetic and pharmacodynamic properties of compounds. These models can be used to predict the interaction between a substance and a drug, including how it affects the drug's concentration in the bloodstream over time.
For example, in silico mathematical models have been developed to predict the pharmacokinetic attributes of compounds before they are synthesized. There are also commercial software programs available that can simulate pharmacokinetic parameters, such as MetabolExpert® and GastroPlus®.
While in silico models are useful for high-throughput screening and can save time and effort, they may not always accurately represent real circumstances. Therefore, it is important to validate the results of simulations with observations and experiments on actual living organisms or tissues.