Final answer:
Enzymes speed up reactions without being consumed by specifically lowering the activation energy, and their activity is sensitive to pH and temperature, but they do not change the reaction's equilibrium.
Step-by-step explanation:
Regarding the question about which statement is not true about enzymes, the correct answer is that enzymes do not change the equilibrium of a reaction. Enzymes are biological catalysts that accelerate chemical reactions by lowering the activation energy. They accomplish this by providing a platform where reactants, also known as substrates, can be brought together to react more readily. By binding to substrates at their active site with specificity, enzymes facilitate reactions without being consumed in the process. Moreover, it is well-known that their activity can be influenced by external conditions such as pH and temperature. At very high temperatures or unsuitable pH levels, enzymes can become inactive due to the denaturation of their protein structure, which disrupts the functional conformation of their active site.