Final answer:
All the provided options A, B, C, and D involve some form of comparative analysis, which is integral to scientific research methods. Therefore, none of the options listed fails to represent a comparative analysis, making the answer E, 'None of these'.
Step-by-step explanation:
The question asks which option is not a comparative analysis. Comparative analysis, in scientific research, often involves comparing different interventions or treatments to evaluate their effectiveness or differences. Option A (Comparing an intervention with refinements to its original form) represents a controlled experiment where a new variant of an intervention is tested against the original. Option B (Comparing two novel interventions to see if they work) and Option C (Comparing competing interventions to determine which one is more effective) both describe scenarios where interventions are compared either to each other or to a known measure, which is a fundamental part of testing a hypothesis by experiment. Option D (Comparing a novel intervention to a well-researched, effective intervention) depicts an observational study, where the outcomes of a new intervention are compared against established results. None of these options strictly represent making a hypothesis or rejecting the old hypothesis and making a new one, which are conceptual steps in the scientific method rather than comparative analyses themselves. Therefore, the answer is E (None of these), as all provided options (A, B, C, D) allude to some form of comparative analysis used for evaluating and testing interventions.