Question

Approximately how many subjects generally participate in phase I studies?

a) 10-100
b) 100-1,000
c) 1,000-10,000
d) 10,000 and above

Answer 1

Phase I studies generally involve 10 to 100 subjects.

Step-by-step explanation:

In Phase I studies, the number of subjects generally ranges from 10 to 100 (option a).

This phase focuses on evaluating the safety, tolerability, and pharmacokinetics of a new drug in a small number of healthy volunteers or patients.

The National Library of Medicine's clinical trials data indicate that there are ongoing clinical trials with a range of subjects, but the typical number of subjects in Phase I studies falls within the given range.