Final answer:
The civilization of the Yellow River in China was markedly different from the Indus Valley Civilization due to the difficulties it faced in controlling flooding for irrigation.
Step-by-step explanation:
The earliest civilization of which region was very different from the Indus Valley model is C) China; Yellow River. The Yellow River civilization, often referred to as the cradle of Chinese civilization, had a significant difference compared to the Indus Valley Civilization due to its severe flooding and the resulting difficulties in controlling water for irrigation. The typography of China, particularly along the Yellow River, involved harsher landscapes with a rapid flow of water from the Himalayas leading to torrential floods. This made the development of their agricultural practices and societal organization distinct from those found in the Indus Valley, where urban planning and the use of water were more systematic and controlled.