Question

Which of the following steroids, when applied topically, is MOST likely to cause in INCREASE in intraocular pressure (IOP)?

-Dexamethasone
-Rimexolone
-Fluorometholone
-Loteprednol

Answer 1

Dexamethasone is the steroid among those listed that is most likely to cause an increase in intraocular pressure when applied topically, potentially leading to glaucoma, especially in individuals over 40.

Step-by-step explanation:

The question pertains to which topical steroid is most likely to cause an increase in intraocular pressure (IOP), potentially leading to glaucoma. Dexamethasone, when applied topically, is more potent and thus more likely to cause an increase in IOP compared to less potent steroids such as Rimexolone, Fluorometholone, and Loteprednol. People over 40 should have their IOP tested routinely to detect and control high intraocular pressures. Topical corticosteroids, like hydrocortisone, are known to reduce inflammation and relieve symptoms by downregulating the immune response. However, the more potent the steroid, the higher the risk of side effects, including raised IOP.