Final answer:
Tetracycline is not recommended for children due to its adverse effect on skeletal growth and potential to cause permanent tooth discoloration.
Step-by-step explanation:
Tetracycline should not be prescribed to children because of the potential adverse effect of depressed skeletal growth. Tetracyclines, including drugs such as doxycycline and tigecycline, inhibit bacterial protein synthesis by preventing the attachment of transfer RNA-amino acid to the ribosome, but they can also affect the host's cells. When given to children, whose bones and teeth are still developing, tetracyclines can lead to permanent discoloration of developing teeth and may adversely influence bone growth, potentially causing conditions like rickets or bone pain due to inhibited protein synthesis required for growth.