78.9k views
1 vote
A patient's laboratory results indicate that the predialysis BUN level was lower than the post dialysis BUN level. When interpreting these findings the technician should seek the answer to which of these questions

-Was the machine in bypass during the post sampling?
-Was the patient's heparin pump turned off when the post sample was drawn?
-Was the predialysis sample drawn from the venous port?
-Was the port used for predialysis sampling cleaned with disinfectant?

1 Answer

3 votes

Final answer:

A lower predialysis BUN level than the post-dialysis BUN level suggests potential technical errors in the dialysis process or sampling methods. The dialyzer should have a concentration gradient to allow diffusion with a higher concentration of solutes in the blood than in the dialysate. An investigation into these technical aspects would be necessary to resolve the unexpected lab result.

Step-by-step explanation:

The question pertains to the unlikely scenario where a patient's laboratory results show a lower predialysis blood urea nitrogen (BUN) level than the post-dialysis BUN level. Normally, dialysis is expected to reduce the BUN levels as urea is one of the waste products removed during the process. Several possible errors can explain the anomaly in the BUN levels.

The interpretation of these findings could be influenced by technical issues, such as if the machine was in bypass during the post sampling, potentially meaning no dialysis actually occurred. The post-dialysis BUN sample should ideally show lower levels of urea, as the dialysis machine works to filter out waste products such as urea from the blood. Hemodialysis typically removes waste products and excess water by passing the patient's blood through a semipermeable membrane where these wastes diffuse into the dialysate.

For hemodialysis to successfully remove wastes from the blood, the concentration of solutes in the upper component of the dialyzer, which contains the patient's blood, is typically higher than that in the lower compartment, which contains the fresh dialysate. This concentration gradient across the semipermeable membrane allows for the diffusion of urea from the blood into the lower component with fresh dialysate. The efficiency and effectiveness of this extraction process depends on a well-functioning machine and correct sampling procedures.

User Michael Kenzel
by
8.5k points