Question

52 y/o with h/o unipolar depression is brought to ED with a first episode of catatonia. Patient is on no meds, UDS is neg. Further w/u should initially focus on what factor?

Answer 1

The initial focus of further work-up for a 52-year-old patient with a history of unipolar depression presenting with catatonia should be determining the possible causes of catatonia in this context.

Step-by-step explanation:

The initial focus of further work-up for a 52-year-old patient with a history of unipolar depression presenting with a first episode of catatonia and no medication use would be to determine the possible causes of catatonia in this context. There are several potential factors to consider, including medical conditions such as metabolic disorders, autoimmune diseases, and neurological disorders.

In addition, other psychiatric conditions like psychotic disorders, substance-induced catatonia, and mood disorders can also present with catatonia. Therefore, a comprehensive evaluation including laboratory tests, imaging studies, and a thorough psychiatric assessment should be conducted to identify the underlying cause.

By ruling out other medical and psychiatric conditions, a more accurate diagnosis can be made, leading to appropriate treatment and management strategies for the patient.