Final answer:
Anterior capsulotomy and/or cingulotomy are indicated and demonstrated effective for patients with severe incapacitating disorder of resistant major depressive disorder (MDD). These surgical interventions involve the destruction or disruption of specific brain regions to alleviate symptoms of depression.
Step-by-step explanation:
Anterior capsulotomy and/or cingulotomy are indicated and demonstrated effective for patients with severe incapacitating disorder of resistant major depressive disorder (MDD).
These surgical interventions, performed on the brain, are considered as treatment options when MDD does not respond to other forms of treatment like medication and therapy. They involve the destruction or disruption of specific brain regions to alleviate symptoms of depression and improve the patient's quality of life.