Question

Proteases are enzymes that play an important role in the digestion of protein. BLANK and BLANK proteases that are secreted in an inactive form by the pancreas and activated by a different enzyme secreted by the small intestine.

Answer 1

Trypsin and chymotrypsin are proteases secreted in their inactive forms by the pancreas and activated in the duodenum by enteropeptidase, facilitating protein digestion without harming the pancreas.

Step-by-step explanation:

Proteases are enzymes that play a crucial role in protein digestion, breaking down proteins into peptides and amino acids. The pancreas secretes proteases like trypsinogen and chymotrypsinogen in their inactive forms to prevent self-digestion, a condition known as pancreatitis. Once in the duodenum, trypsinogen is activated into trypsin by the intestinal brush border enzyme enteropeptidase. Trypsin then activates other proteases such as procarboxypeptidase and chymotrypsinogen into their active forms, carboxypeptidase, and chymotrypsin, respectively. These activated enzymes facilitate further breakdown of protein into absorbable amino acids within the small intestine.