Final answer:
The statement is false; DNA replication origins are typically rich in adenine-thymine base pairs, not guanine-cytosine. AT pairs are easier to separate due to having fewer hydrogen bonds, which aids the initiation of DNA replication.
Step-by-step explanation:
The statement "DNA replication origins are typically rich in G-C base pairs." is false. Origins of replication in DNA are actually rich in adenine-thymine (AT) base pairs. This is because AT base pairs have only two hydrogen bonds (compared to the three hydrogen bonds of cytosine-guanine (CG) base pairs), which makes them easier to separate during the initiation of DNA replication. For example, in Escherichia coli (E. coli), the origin of replication called oriC is specifically rich in AT sequences, facilitating the unwinding of the DNA helix. This is an important aspect of the process, as replication begins at these origins and the enzymes involved in DNA replication must be able to access the single-stranded DNA.