Question

DNA Polymerases Have a Common Structure

DNA polymerases fall into five families. The ____ is the most conserved domain, and the thumb and fingers differ between the families. DNA binds in the cleft between ____ and ____.

Answer 1

The palm domain is the most conserved domain in DNA polymerases, DNA binds in the cleft between the palm and thumb, and between the palm and fingers. DNA polymerase plays a critical role in DNA synthesis and repair in prokaryotes.

Step-by-step explanation:

DNA polymerases fall into five families. The palm domain is the most conserved domain, and the thumb and fingers differ between the families. DNA binds in the cleft between the palm and thumb and between the palm and fingers. The role of DNA polymerase goes beyond replication, including proofreading and repairing DNA. In prokaryotes, DNA polymerase is composed of several subunits, with DNA polymerase III being the primary enzyme required for DNA synthesis, while DNA polymerase I and DNA polymerase II are primarily involved in repair processes.