Question

The oriC is fully methylated

The origin has three 13 bp repeats

DnaA monomers bind at 9 bp repeats

DnaA binds to 13-bp repeats

DNA strands separate at 13 bp repeats

DnaB/DnaC joins complex forming ___

Answer 1

The replication machinery knows where to begin based on specific nucleotide sequences called origins of replication. Proteins bind to these origins of replication and helicase unwinds and opens up the DNA helix to form replication forks, allowing replication to proceed in both directions.

Step-by-step explanation:

The replication machinery knows where to begin based on specific nucleotide sequences called origins of replication. In E. coli, the origin of replication is approximately 245 base pairs long and is rich in AT sequences. Proteins recognize and bind to the origin, and an enzyme called helicase unwinds and opens up the DNA helix, forming Y-shaped structures called replication forks. Replication forks extend bi-directionally from the origin as replication proceeds. Single-strand binding proteins coat the single strands of DNA near the replication fork to prevent them from winding back into a double helix.